Newborn histone modifications and gestational exposure to particulate matter air pollution
نویسندگان
چکیده
منابع مشابه
Mitochondrial oxidative DNA damage and exposure to particulate air pollution in mother-newborn pairs
BACKGROUND Studies emphasize the importance of particulate matter (PM) in the formation of reactive oxygen species and inflammation. We hypothesized that PM exposure during different time windows in pregnancy influences mitochondrial 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels, which is an established biomarker for oxidative stress, in both maternal and foetal blood. METHODS We investigated m...
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With 2.8 billion biomass users globally, household air pollution remains a public health threat in many low- and middle-income countries. However, little evidence on pollution levels and health effects exists in low-income settings, especially slums. This study assesses the levels and sources of household air pollution in the urban slums of Nairobi. This cross-sectional study was embedded in a ...
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BACKGROUND Air pollution is a pervasive environmental health hazard that occurs over a lifetime of exposure in individuals from many industrialized societies. However, studies have focused primarily on exposure durations that correspond to only a portion of the lifespan. We therefore tested the hypothesis that exposure over a considerable portion of the lifespan would induce maladaptive cardiov...
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BACKGROUND Long-term exposure to urban air pollution may accelerate atherogenesis, but mechanisms are still unclear. The induction of a low-grade systemic inflammatory state is a plausible mechanistic pathway. OBJECTIVES We analyzed the association of residential long-term exposure to particulate matter (PM) and high traffic with systemic inflammatory markers. METHODS We used baseline data ...
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MY JOB AND UNIT IN WHICH I WORK The research presented here was conducted at the Division of Child Health at the University of Leicester (Leicester, UK). I was a research fellow on the project supervised by Professor Jonathan Grigg. Professor Grigg (who has been presented with the Occupational and Environmental Best Paper Annual Award 2007 by the European Respiratory Society) is currently based...
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ژورنال
عنوان ژورنال: Environmental Epidemiology
سال: 2019
ISSN: 2474-7882
DOI: 10.1097/01.ee9.0000610684.93852.e6